ANSWER KEY WITH HINT - PHARMA SOLUTION NEPAL

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ANSWER KEY WITH HINT

 ANSWER KEY WITH HINT



Que

 No.

Answer

Explanation

1

C. Increased metabolism

Rifampicin increases liver enzymes that metabolize oral contraceptives faster, reducing their effect.

2

B. Phospholipid synthesis

Magnesium is not primarily involved in phospholipid synthesis but in nerve conduction, muscle function, and metabolism.

3

B. 1000 ppm

0.1% alcohol = 1000 parts per million (ppm).

5

D. Confirmation of symptoms can be skipped

Confirming symptoms is essential for an accurate diagnosis. It should not be skipped.

7

A. 30°C ±2°C/60%RH ± 5%RH

This is the standard real-time stability testing condition in Nepal.

9

D. Should be designed and constructed to facilitate good sanitation.

Premises should be designed for cleanliness to prevent contamination.

12

B. Senna

Senna is a well-known source of anthraquinones, which are used for their laxative effects.

13

B. Mandoor

Mandoor is an Ayurvedic formulation that requires assay for iron content.

14

C. Zanthoxylum armatum

Timur is the common name for Zanthoxylum armatum (Sichuan pepper).

15

A. Leguminosae

Senna belongs to the legume family (Leguminosae).

16

D. Acorus calamus

Sweet Flag is the common name for Acorus calamus.

17

A. Valeriana jatamansi

Padamchal is the common name for Valeriana jatamansi, used in traditional medicine.

18

B. Molisch

Molisch's test is used to identify carbohydrates through a reaction forming a purple ring.

19

B. Fructose

Fructose is one of the main sugars found in honey.

20

A. Decoction

A decoction is made by boiling the drug in water to extract active compounds.

21

A. Those that are sensitive to the terminal sterilization process

Sterile filtered products cannot undergo terminal sterilization due to heat sensitivity.

22

C. Should be crossed through with a single line and initialed or signed, dated, and if appropriate, the reason recorded.

Correct documentation procedures require single-line crossing and proper records.

23

B. Should be designed so that it can be easily and thoroughly cleaned on a scheduled basis.

Equipment should be easy to clean to prevent contamination.

24

D. In controlled medicines safe

Morphine is a controlled substance and should be stored in a locked, secure safe.

25

D. At night

Simvastatin is best taken at night since cholesterol synthesis primarily occurs during sleep.

26

B. 400-100 nm

UV spectroscopy typically involves wavelengths between 200-400 nm.

27

B. Changes in rotational and vibrational energy states.

In infrared spectroscopy, absorption leads to changes in molecular vibrational and rotational states.

28

B. NMR

NMR spectroscopy involves interaction with nuclei, not electrons, unlike UV or IR spectroscopy.

29

D. Solid, liquid, or gas, any state of sample.

Mass spectrometry can analyze samples in any state—solid, liquid, or gas.

30

A. Weak interaction

Gas chromatography involves weak interactions between the analyte and mobile phase (gas).


PHARMA SOLUTION NEPAL

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