ANSWER KEY WITH HINT
Que No. |
Answer |
Explanation |
1 |
C. Increased
metabolism |
Rifampicin
increases liver enzymes that metabolize oral contraceptives faster, reducing
their effect. |
2 |
B.
Phospholipid synthesis |
Magnesium is
not primarily involved in phospholipid synthesis but in nerve conduction,
muscle function, and metabolism. |
3 |
B. 1000 ppm |
0.1% alcohol
= 1000 parts per million (ppm). |
5 |
D.
Confirmation of symptoms can be skipped |
Confirming
symptoms is essential for an accurate diagnosis. It should not be skipped. |
7 |
A. 30°C
±2°C/60%RH ± 5%RH |
This is the
standard real-time stability testing condition in Nepal. |
9 |
D. Should be
designed and constructed to facilitate good sanitation. |
Premises
should be designed for cleanliness to prevent contamination. |
12 |
B. Senna |
Senna is a
well-known source of anthraquinones, which are used for their laxative
effects. |
13 |
B. Mandoor |
Mandoor is an
Ayurvedic formulation that requires assay for iron content. |
14 |
C.
Zanthoxylum armatum |
Timur is the
common name for Zanthoxylum armatum (Sichuan pepper). |
15 |
A.
Leguminosae |
Senna belongs
to the legume family (Leguminosae). |
16 |
D. Acorus
calamus |
Sweet Flag is
the common name for Acorus calamus. |
17 |
A. Valeriana
jatamansi |
Padamchal is
the common name for Valeriana jatamansi, used in traditional medicine. |
18 |
B. Molisch |
Molisch's
test is used to identify carbohydrates through a reaction forming a purple
ring. |
19 |
B. Fructose |
Fructose is
one of the main sugars found in honey. |
20 |
A. Decoction |
A decoction
is made by boiling the drug in water to extract active compounds. |
21 |
A. Those that
are sensitive to the terminal sterilization process |
Sterile
filtered products cannot undergo terminal sterilization due to heat
sensitivity. |
22 |
C. Should be
crossed through with a single line and initialed or signed, dated, and if
appropriate, the reason recorded. |
Correct
documentation procedures require single-line crossing and proper records. |
23 |
B. Should be
designed so that it can be easily and thoroughly cleaned on a scheduled
basis. |
Equipment
should be easy to clean to prevent contamination. |
24 |
D. In
controlled medicines safe |
Morphine is a
controlled substance and should be stored in a locked, secure safe. |
25 |
D. At night |
Simvastatin
is best taken at night since cholesterol synthesis primarily occurs during
sleep. |
26 |
B. 400-100 nm |
UV spectroscopy
typically involves wavelengths between 200-400 nm. |
27 |
B. Changes in
rotational and vibrational energy states. |
In infrared
spectroscopy, absorption leads to changes in molecular vibrational and
rotational states. |
28 |
B. NMR |
NMR
spectroscopy involves interaction with nuclei, not electrons, unlike UV or IR
spectroscopy. |
29 |
D. Solid,
liquid, or gas, any state of sample. |
Mass
spectrometry can analyze samples in any state—solid, liquid, or gas. |
30 |
A. Weak
interaction |
Gas chromatography
involves weak interactions between the analyte and mobile phase (gas). |
PHARMA SOLUTION NEPAL
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